Started NDGA today. 50mg daily to begin. It ranks 36th in wild type mouse lifespan studies

Well SupportedNDGA showed a 13% increase in medium lifespan and a 7% increase in maximum lifespan in mouse studies.

Not SupportedNDGA at 2g daily was used in a trial for prostate cancer, but doses as low as 100-500mg may cause sub-clinical liver or kidney damage.

Partially SupportedThe long-term safety of NDGA is being assessed for potential sub-clinical liver or kidney damage.

Partially SupportedNDGA is a lignan, a class of organic compounds found in certain plants, and is a potential autophagy enhancer.

Partially Supported