The lipid hypothesis is flawed and incomplete. Not all ‘elevations’ of ApoB carry increase

Not SupportedMetabolic health context is crucial for understanding atherosclerosis, not just LDL's direct injury to the endothelium.

Well SupportedImpaired wound healing at the endothelial level in individuals with insulin resistance prevents proper repair, leading to the initiation of atherosclerosis.

Partially SupportedApob levels rise with age, but not significantly enough to be the sole indicator of risk.

Partially SupportedElevated LDL/ApoB from consuming steak and seed oils is not a concern for individuals who are insulin sensitive, metabolically healthy, and do not have familial hypercholesterolemia.

Partially Supported