I took one of the world's most promising anti-aging drugs and accidentally made myself old

Not SupportedBryan Johnson stopped taking rapamycin after four years due to negative effects on lipids, blood glucose, resting heart rate, and small tissue infections.

Partially SupportedBryan Johnson tested weekly (5, 6, and 10 mg), biweekly (13 mg), and alternating weekly (6/13mg) rapamycin dosing schedules.

Not SupportedRapamycin's inhibition of natural killer cells raises concerns about anti-cancer immune surveillance and increased cancer risk.

Not SupportedProlonged rapamycin use can disrupt lipid metabolism, induce insulin and glucose intolerance, and cause pancreatic beta-cell toxicity.

Partially Supported