DNA breaks are a potent accelerator of epigenetic drift, which some researchers think driv

Well SupportedInducing DNA breaks without causing mutations or cancer leads to aging phenotypes in mice.

Partially SupportedBowhead whales produce high levels of the DNA-repair protein CIRBP.

Partially SupportedStrengthening DNA repair mechanisms may help slow aging and extend healthy human lifespan.

Partially SupportedIncreasing CIRBP levels in fruit flies extended lifespan and improved resistance to radiation damage.

Partially SupportedCIRBP improves the repair of DNA double-strand breaks, which are a source of mutations, cancer, and aging.