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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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How to mitigate cognitive decline in middle age | Peter Attia and Tommy Wood — Whalespan

Content›Video›How to mitigate cognitive de…

How to mitigate cognitive decline in middle age | Peter Attia and Tommy Wood

Peter Attia9m · 2024-08-15

Claims Made

14

Claims Supported

13

Support Rate

93%

Support rate

13 of 14 claims supported

13 supported1 partial / not

Claims from this content

9

✓Well SupportedRetiring earlier is associated with earlier cognitive decline.✓Well SupportedReplacing work with cognitively stimulating activities after retirement can mitigate most or all of the risk of cognitive decline associated with stopping work.✓Well SupportedEarly-life education and late-life cognitive activity are the two most important modifiable factors for preventing cognitive decline.◐Partially SupportedCognitively stimulating activities like chess or dancing later in life are protective against dementia.Partially Supported

More from Peter Attia

Peter Attia on Zone 2 Cardio

Peter Attia on Rapamycin (with Matt Kaeberlein)

Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

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Cognitive function increases from birth to a peak in the late teens or early twenties, which is the period of formal education, skill learning, and sports.

◐Partially SupportedCognitive training can lead to significant improvements in cognitive function in older adults.

◐Partially SupportedHyperspecialization in a single skill reduces opportunities for brain plasticity and cognitive headroom.

◐Partially SupportedMaintaining basic cognitive functions requires actively increasing cognitive headroom and capacity throughout the lifespan.

◐Partially SupportedRetirement should be a transition to cognitively demanding activities.