The Holy Grail Metric of Longevity | Peter Attia

Well SupportedVO2 max is the greatest predictor of lifespan, surpassing other biomarkers and health factors like smoking, diabetes, kidney disease, heart disease, and hypertension.

Well SupportedThe mortality reduction benefits of exercise are greater than those from quitting smoking or managing end-stage renal disease.

Well SupportedMoving from below-average to above-average VO2max is associated with a 41% increased risk of all-cause mortality.

Well SupportedIndividuals in the lowest 25% of cardiorespiratory fitness have mortality rates as high as or higher than smokers, individuals with hypertension, or those with diabetes.

Partially Supported