Why do low-fat and low-carb diets lead to weight loss? | Peter Attia & Stephan Guyenet

Well SupportedDesigning a human diet with very low fat intake (around 10% or less) that is palatable for randomized controlled trials is challenging.

Partially SupportedIn animal models, changing diet composition can lead to fat gain independent of total calorie intake.

Partially SupportedThe combination of high fat and high carbohydrate in the diet is problematic for weight management.

Partially SupportedDiets with 10-15% fat intake may offer some health benefits compared to diets in the 'messy middle'.

Partially SupportedCommon starch foods like whole wheat and corn contain a significant amount of fat, making very low-fat diets challenging.