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Rapamycin extends mouse lifespan 9–14%
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What are Peter's thoughts on alcohol consumption and health? (Qualy #1) — Whalespan

Content›Video›What are Peter's thoughts on…

What are Peter's thoughts on alcohol consumption and health? (Qualy #1)

Peter Attia12m · 2020-02-11

Claims Made

19

Claims Supported

9

Support Rate

47%

Support rate

9 of 19 claims supported

9 supported10 partial / not

Claims from this content

16

✓Well SupportedAlcohol fragments sleep by causing brief awakenings throughout the night, which measurably impact sleep physiology and overall wellness.✓Well SupportedOne alcoholic drink in the evening does not impact sleep, but two or more drinks profoundly increase resting heart rate and decrease heart rate variability.✓Well SupportedAlcohol suppresses REM sleep at all doses, reducing its crucial role in long-term memory formation.◐Partially SupportedA standard drink is defined as 12 oz beer, 5 oz wine, or 1-1.5 oz hard liquor.Partially Supported

More from Peter Attia

Peter Attia on Zone 2 Cardio

Peter Attia on Rapamycin (with Matt Kaeberlein)

Attia walks back the clinic protocol: too aggressive for healthy adults

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AV

A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

NP

N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

Ethanol is a toxin whose impact on a population follows a probability distribution.

✕Not SupportedResveratrol has not been shown to affect the biology of aging or act as a longevity drug.

✕Not SupportedAlcohol has no biochemical requirement in the body and has not been observed to improve any important function.

◐Partially SupportedPeter Attia's rule is to consume only high-quality, exceptional alcohol for a specific purpose.

◐Partially SupportedAlcohol consumption can lead to behaviors such as loosening control over eating habits.

◐Partially SupportedSome individuals exhibit genetic outlier tolerance to alcohol, maintaining normal liver function despite consuming very high quantities.

◐Partially SupportedEthanol's effect on the central nervous system is experienced as a 'buzz' and CNS depression, acting as a GABA agonist.

◐Partially SupportedAldehyde, a byproduct of ethanol metabolism, is a toxin that affects both the liver and the brain.

◐Partially SupportedThe liver's metabolic pathway for ethanol overlaps significantly with that of sugar or fructose.

◐Partially SupportedA single glass of wine per day might offer a net benefit by reducing cortisol and emotional distress.

◐Partially SupportedALT (alanine transaminase) is the best proxy for assessing current liver function, and levels above 20 are considered abnormal.

✕Not SupportedThe French paradox is likely explained by factors other than red wine, such as diet and smoking habits.