Can Stem Cells Regenerate the Injured Brain? | Edward Chang, M.D.

Partially SupportedSynthetic cells could be engineered to produce dopamine for treating conditions like Parkinson's disease.

Partially SupportedNewer cell therapies for Parkinson's disease utilize improved cell models and delivery systems for better control over dopamine release.

Partially SupportedFocal delivery to replace lost cells in small brain targets, such as dopamine-producing neurons in Parkinson's disease, is the most promising near-term application of cell-based therapies for CNS regeneration.

Partially SupportedBiological therapy engineering is increasingly focused on minimizing immunogenicity to avoid transplant rejection.

Partially SupportedPrevious fetal-derived cell transplants for Parkinson's disease caused hyperkinesia due to uncontrolled dopamine release.