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Rapamycin extends mouse lifespan 9–14%
NAD+ precursors reverse aging in humans
Blue-light glasses improve sleep quality
Walking 10 min after meals blunts glucose
Verdict change — caffeine half-life downgraded

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What is medicine 3.0? — Whalespan

Content›Video›What is medicine 3.0?…

What is medicine 3.0?

Peter Attia12m · 2024-08-01

Claims Made

15

Claims Supported

11

Support Rate

73%

Support rate

11 of 15 claims supported

11 supported4 partial / not

Claims from this content

10

✓Well SupportedMedicine 3.0 prioritizes healthspan over lifespan.✓Well SupportedMedicine 3.0 aims to prevent chronic disease through early, aggressive, and personalized therapies, and to prioritize healthspan equally with lifespan.✓Well SupportedMetabolic diseases like fatty liver disease and type 2 diabetes increase the risk of cardiovascular disease, cancer, and dementia by 25-50%.✓Well SupportedMedicine 3.0 aims to extend the period of life lived without disease, while Medicine 2.0 focuses on extending life after a disease has occurred.Partially Supported

More from Peter Attia

Peter Attia on Zone 2 Cardio

Peter Attia on Rapamycin (with Matt Kaeberlein)

Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

In the era of medicine 1.0, average human life expectancy was in the late 30s or early 40s, with common causes of death being communicable diseases, infections, and complications from childbirth.

◐Partially SupportedThe scientific method, light microscope, germ theory, antimicrobials, and sanitation collectively doubled human lifespan from the late 1800s to the late 1900s.

◐Partially SupportedThe primary causes of death today are atherosclerosis, cancer, and neurodegenerative diseases.

◐Partially SupportedLifespan extension has largely stalled since the period between the Civil War and the end of World War I.

◐Partially SupportedMost healthcare spending in Medicine 2.0 is directed towards extending lifespan rather than improving healthspan.

◐Partially SupportedThe four major categories of chronic diseases contributing to mortality are atherosclerosis (coronary artery disease, cerebral vascular disease), cancer, neurodegenerative diseases (Alzheimer's, Parkinson's, etc.), and metabolic diseases.