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Rapamycin extends mouse lifespan 9–14%
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The major health risks of a sedentary lifestyle — Whalespan

Content›Video›The major health risks of a …

The major health risks of a sedentary lifestyle

Peter Attia1m · 2024-04-23

Claims Made

7

Claims Supported

7

Support Rate

100%

Support rate

7 of 7 claims supported

7 supported0 partial / not

Claims from this content

7

✓Well SupportedImmobilization of legs for two weeks can result in nearly 15% loss in quadricep muscle cross-sectional area.✓Well SupportedReducing physical activity for two weeks can cause anabolic resistance and reduce insulin sensitivity in older adults.◐Partially SupportedA muscle-centric view is important for aging because movement cessation leads to physiological system deterioration.◐Partially SupportedInsulin sensitivity declines with one week of inactivity, along with other markers of cardiovascular and metabolic health.Partially Supported

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Peter Attia on Zone 2 Cardio

Peter Attia on Rapamycin (with Matt Kaeberlein)

Attia walks back the clinic protocol: too aggressive for healthy adults

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A. Volkovreader

4h

Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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N. Park

2d

Would love a "what would change this verdict" RSS feed. Sign me up if it exists.

◐

One week of inactivity in healthy young people leads to a significant decline in oxidative capacity and insulin sensitivity, alongside muscle loss.

◐Partially SupportedSedentary behavior leads to accelerated deterioration of cardiovascular and brain systems.

◐Partially SupportedInactivity leads to a decline in quality of life, happiness, and well-being.