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Benefits hold across the populations where it's been tested.
Benefits hold across the populations where it's been tested.
Mechanistic and trial evidence converge on a real, replicable effect.
Mechanistic and trial evidence converge on a real, replicable effect.
The effect size is large enough to matter clinically, not just statistically.
The headline effect shrinks once you account for trial quality.
Animal-model results don't translate to the human protocol being recommended.
Confounding and publication bias inflate the apparent benefit.
Most of the support comes from short or small studies.
The headline effect shrinks once you account for trial quality.