Paul Saladino· MD
but this is the test you want if you want to get oxidized ldl you do not want ox ldl from cleveland heart labs
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
but this is the test you want if you want to get oxidized ldl you do not want ox ldl from cleveland heart labs
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so remember this five middle is 5.0 to 7.5 to uh yeah 7.5 and above is increased risk right there's a lot of great studies on this
99 of the oxidized ldl tests are not really valid because the one from cleveland heart lab is a true false it's a boolean test which is really only going to tell you if an ldl particle an ldl sphere a phospholipid has an a certain threshold of phospholipids that are oxidized that will be a positive what dave wanted to find was a test that was actually representative of the percentage of the phospholipids across that spherical ldl particle that were oxidized but it's not it's a is so let me correct you real quick this is actually quantitative quantitative so that's going to be important later that's going to be important later it's it's as if you were to for a given unit of blood count the oxidized phospholipids the ox pl on apob apob containing lipoproteins as opposed to just a metric that looks at sort of a boolean true false metric of how many ldl particles are oxidized which as you said really just tracks with your ldl particle number not a perfect test this is a totally different test
this oxfoss the lipids on ldl is really valuable
oxidized phospholipids on apob which will give you a much better sense of oxidized ldl than a traditional oxidized ldl test traditional oxidized ldl tests are really inaccurate again they're just a they're just a proxy for apob and um the ldl number
there's another metric you can get from a lab called boston heart called oxidized phospholipids on apob which will give you a much better sense of oxidized ldl than a traditional oxidized ldl test traditional oxidized ldl tests are really inaccurate again they're just a they're just a proxy for apob
I think that today the best test we have is the LP little a particle number and there's a proxy for it but I'm guessing we'll talk about that later which is you can also measure the amount of oxidized phospholipid if you normalize that for a Bobi you're getting almost a one-to-one mapping of that
if you measure those phospholipids normalized for a poby you're getting a pretty good proxy also of that