Andrew Huberman· PhD
I think in reasonable amounts provided we can still fall asleep at night, caffeine can be a relatively safe way to increase epinephrin.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
I think in reasonable amounts provided we can still fall asleep at night, caffeine can be a relatively safe way to increase epinephrin.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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Indeed caffeine can increase epinephrine and dopamine to some extent, but most people are drinking it chronically. So its effects are probably due to increases in epinephrine and probably whether or not something like coffee or other forms of caffeine can improve or degrade your immune system will probably depend on whether or not you're using it in a way that it increases your adrenaline as a spike, that happens rarely, you know, once every two or three months, let's say you have an infection coming on, yes indeed.
ingestion of caffeine will tap into and support dopamine and epinephrine.