Andrew Huberman· PhD
Basically coffee gives you energy it makes you feel good and it increases focus because of the circuits that it engages in the brain.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Basically coffee gives you energy it makes you feel good and it increases focus because of the circuits that it engages in the brain.
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Caffeine, which I can indulge some, I don't think to access has long been used as a stimulant to increase dopamine, increase norepinephrine, increased focus and energy and in addition to that, it works through the so-called cyclic amp, phosphodiesterase pathway, remember anytime you see, you hear an ASE, that's an enzyme. Phosphodiesterase is involved in the conversion of things like cyclic amp into energy for cells and so forth. Basically coffee gives you energy it makes you feel good and it increases focus because of the circuits that it engages in the brain.
caffeine is increasing dopamine's function by changing the number and efficacy of dopamine receptors, but of course, it also increases our wakefulness, our alertness, and that is largely through the neurochemical systems related to adenosine, which is a molecule that builds up in our brain and body the longer we are awake, it's part of the sleepiness system if you will, it makes us feel fatigued or tired, and caffeine also operates on the epinephrine, the adrenaline system.
Because caffeine increases the catecholamines and in particular because caffeine increases dopamine transmission in the prefrontal cortex-- this area of the brain that's associated with focus and rule setting and context and task switching-- caffeine is known to improve focus and alertness, in particular, in people who have symptoms of ADHD or other attention and focus issues.