The problem is if you inherit a broco mutation as an individual you have a very high risk of developing cancer. So it as an individual your risk goes way way up and of certain types of cancer in particular
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
The problem is if you inherit a broco mutation as an individual you have a very high risk of developing cancer. So it as an individual your risk goes way way up and of certain types of cancer in particular
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
as you know um brca 102 increased the risk of prostate cancer in men uh they also increase the risk of male breast cancer and they also increase the risk of pancreatic cancer though the numerical issues there are all smaller than than the risk of breast or ovarian cancer
brca1 and brca2 are very high penetrant genes that means there's a pretty high lifetime risk of developing breast cancer or ovarian cancer if you have a brca 1 or brca2 mutation
if the average again we've talked about this number at one and eight instead of one and8 we're talking about you know a one and two or even a two and three chance lifetime of developing breast cancer for women who Harbor those gene mutations
Whole-body MRI screening in healthy adults produces more incidentaloma harm than cancer-mortality benefit.
Starting colonoscopy screening at 45 (vs 50) prevents enough early-onset cancers to justify the population cost.
Multi-cancer liquid-biopsy tests like Galleri detect early cancers at a stage that meaningfully improves survival.