The mutations that cause cancer are typically acquired somatic mutations, not inherited, except in cases like Lynch syndrome.

“so question one is how much of cancer results from those types of genetic mutations and the answer is very little less than 5%”

“cancer is a genetic disease in the sense that every Cancer has genetic mutations um most of those mutations are sematic which means most of those mutations are mutations that occur during the course of our life they're not germline mutations the germline being the uh eggs and sperm right so it's all other cells”

“I mean I think everybody agrees that most cancers involve somatic mutations you know they're very few cancers that involve germline mutations that's those are the those are the exceptions but the the general one is these are required mutations”

“these aren't typically mutations that people are born with although in diseases like Lynch syndrome that might be the case that it leads to that but but for these are acquired mutations”

“cancer is a genetic disease in the sense that every cancer has genetic mutations um most of those mutations are sematic which means most of those mutations are mutations that occur during the course of our life they're not germline mutations the germline being the uh eggs and sperm right so it's all other cells”