David Sinclair· PhD
Quitting smoking causes a decrease in lung ACE2 levels, which can explain why smokers are susceptible to severe SARS-CoV-2 infections.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Quitting smoking causes a decrease in lung ACE2 levels, which can explain why smokers are susceptible to severe SARS-CoV-2 infections.
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A: Chronic smoke exposure triggers expansion of mucus-secreting goblet cells and an increase in ACE2. Quitting smoking causes a decrease in lung ACE2 levels, which can explain why smokers are susceptible to severe SARS-CoV-2 infections.
Chronic smoke exposure triggers expansion of mucus-secreting goblet cells and an increase in ACE2.