Andrew Huberman· PhD
what you end up with is a situation in which you have inflammation in multiple places in the brain and body and the desire to drink even more and to further exacerbate that inflammation and the gut leakiness. So this is basically a terrible scenario for the gut-liver-brain axis, and it's especially prevalent in so-called alcohol use disorder, again, people that are ingesting somewhere between 12 and 24 drinks per week.