Negative experiences can lead to robust, one-trial learning due to a massive release of norepinephrine and epinephrine.

“your nervous system is wired such neuroplasticity is such that stressful experiences because they deploy such massive amounts of adrenaline epinephrine as well as other neuromodulators allow very quickly for the milu the environment of the neural circuits that led up to that experience to strengthen their connections with one trial so-call one trial learning”

“whereby you know this thing I said earlier you know the brain only changes under conditions where norepinephrine and epinephrine are released you know there is such a thing as one trial learning and it's associated with negative experiences and the reason negative experiences create such robust learning in only one trial is because there's a massive amount of epinephrine and norepinephrine and other neurochemicals released so it's stamped into the nervous system”