Andrew Huberman· PhD
And so we know, and if you do that over visual cortex, you don't get that, or motor cortex, you don't get any of those findings. It's really specific to this kind of control region of the brain.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
And so we know, and if you do that over visual cortex, you don't get that, or motor cortex, you don't get any of those findings. It's really specific to this kind of control region of the brain.
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If you measure heart rate in standard ways that cardiologists measure heart rate and you stimulate over this left dorsolateral, you get a deceleration of the heart rate and it's very time locked to the stimulation. So it's a two second train of stimulation. At one second, you see the deceleration, it goes down about 10 beats per minute, and then it'll drift back up and there's a break for eight seconds on the stimulation. Drifts back up and the stimulation goes back in and then the heart rate goes back down. And so you see the heart rate just do this, 10 beats per minute every train.
So the heart very consistently seems to be the end organ of the dorsolateral prefrontal cortex.
And if you do that in the actual scanner, which we can do, you can see that that distributes down into the anterior cingulate and the insula and the amygdala. And ultimately the tract goes into something called the nucleus tractus solitarius and ultimately into the vagus nerve into the heart.
This is also a pathway that you want to keep tuned up, that is, that you'll want to make sure is activated on a pretty frequent basis, and it's super easy to do as you'll soon see, so that the pathway does not deteriorate.