Paul Saladino· MD
I am a big advocate for what I would call environmental hormesis over molecular where Mises which we may or may not have time to talk about today
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
I am a big advocate for what I would call environmental hormesis over molecular where Mises which we may or may not have time to talk about today
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I do agree that exercise he cold even fasting to some extent activate nrf2 there are these environmental hor medics right and nrf2 has this protein keep one which keeps it dormant and when you when you degrade keep one nrf2 does its thing
the same thing that's happening with the cold water swimmers and there's other good research showing that exercise effects nrf2 heat effects nrf2 we know that cold does with the berlin cold water swimmers and ketosis can also affect the nrf2 system
environmental hermetics are things like ketosis fasting sunlight exercise heat stress cold stress these can create oxidative stress in the human body and turn on nrf2 but they don't have collateral effects because they generally don't involve an exogenous and outside of the body's molecule