Turns out it's beneficial for the bone as well.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Turns out it's beneficial for the bone as well.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
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I've been recommending this to patients for 6 months now. The big shift is patients actually do it because the explanation is concrete.
Same in nutrition counseling. The before/after framing helps.
Tracking with a CGM on top of this for 3 months. Variability dropped quickly and stayed dropped.
Worth noting the 0.71 SMD in the Kreider meta is in trained athletes. Effect in untrained adults runs closer to 0.3 — still meaningful, but the panel should reflect that gradient.
Good catch. Could the brief surface the training-status interaction inline?
If you go to 10 grams of creatine per day, boom, two scoops. 10 grams of creatine per day appears to be helpful for bone loss. So, if you or someone you know has osteopenia or osteoporosis here, I'm thinking of my 70 something yearear-old mother and father who have osteopenia, 10 grams of creatine has been shown to improve bone loss, especially when combined with resistance exercise.
Higher doses of creatine than 5 grams a day are also beneficial. 10 grams of creatine per day has been studied for bone loss. And doses of 8 to 10 grams of creatine per day have been shown to slow bone loss and bone resorption, especially if there is some degree of resistance training.
If you’re considering creatine supplementation and want to maximize its effects, a 10-gram daily dose could be worth exploring.
maintains bone density
10 grams per day seems sufficient to optimize muscle/bone/brain health.
it sort of increases osteoblast cells these are these are cells that sort of create uh or the formation of our our bone cells
and we've just shown in a long-term clinical trial and improved bone strength
I would be very surprised I think you need that mechanical loading from weight training or weightbearing exercise Plyometrics that cause the bone to turn over and then maybe creatine doesn't increase the resorptive or it increases osal blast a little bit more
in rodents osteoblast cells have been energized in the presence of creatine so it was logical to think in humans maybe our osteoblast cells the cells that are responsible for increasing bone size and strength might have more fuel and these cells do use creatine just like our muscles do for fuel um and potentially increase bone density
creatine reduces something called the osteoclast activity or bone resorption so for for some reason it really inhibits these osteoclasts from sort of chopping down our bone and increasing blood calcium levels when not needed
we have not shown in a single study an increased bone mineral density so this is really crucial we are not saying that creatine and weight training increases bone mineral density but it certainly decreases bone mineral density loss and really specifically around the hip region which is crucially important for a lot of older adults because when they fall if they land on their hip they could be more susceptible to fracture
and then perhaps in combination with creatine if it's it's really if it's preserving bone that does really suggest a preventative role right
so all the other data 10 gam seems to be a very viable dose to not only check off the Box definitely for muscle we're now checking off the box for brain and now we're or sorry bone and then we're also checking off the the box for uh brain as well
the lowest dose ever been shown to be effective is 8 G of monohydrate a day
5 g of creatine monohydrate daily improves muscle strength and lean mass in healthy adults at standard training loads.
Creatine improves cognitive performance, especially under sleep deprivation and high cognitive load.
Creatine improves cardiovascular health markers and reduces all-cause mortality risk.
Creatine supports bone-mineral density in post-menopausal women when paired with resistance training.
Women need higher creatine doses (8–10 g/day) than men to reach the same intramuscular saturation.