Paul Saladino· MD
Plant molecules have side effects too! 🤯We must not forget about the “package insert” for things like curcumin, resveratrol, sulforphane and others!
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
Plant molecules have side effects too! 🤯We must not forget about the “package insert” for things like curcumin, resveratrol, sulforphane and others!
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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Gotta weigh risks vs benefits- and I don’t think this ever favors benefits!
for every plant molecule that I could find whether it was curcumin Sephora Fane quercetin flavonoids as a general class isothiocyanates all these molecules we could find a benefit somewhere if we just had a very myopic perspective if we just looked at that molecule in one little experiment but whenever anyone had done the experiments to expand the frame these molecules seemed to have side effects in the rest of the body
why would we expect that curcumin pigment polyphenolic pigment in the root of a turmeric plant would be somehow different from that paradigm would break that model would be a molecule that is only beneficial for a human but doesn't have a negative side effect somewhere else ah this is really interesting and the same thing with sulforaphane
i would argue that the majority of the time the risk is not worth or the benefits are not worth the risk
sulforaphane is the same way that and i what i worry about are these collateral side effects if the beneficial effect is something we can get by living well in the first place right it's kind of a redundant effect