Andrew Huberman· PhD
In fact, interestingly, there's been some studies showing that people that are that don't respond to SSRIs are have very high amounts of C reactive protein. So, this was the biomarker for a classical biomarker for inflammation.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
In fact, interestingly, there's been some studies showing that people that are that don't respond to SSRIs are have very high amounts of C reactive protein. So, this was the biomarker for a classical biomarker for inflammation.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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Several studies have shown that people with major depressive disorder have very high levels of inflammation.
For example, the risk of major depression has been shown to increase by 44% for each standard deviation increase in log c-reactive protein.
The significance of this inflammation linked to depression is reinforced by observations that the risk for major depression is increased by 44% for each standard deviation increase in log C reactive protein which is a common measure of systemic inflammation that is also used as a measure of cardiovascular disease risk.
elevated biomarkers of inflammation such as C reactive protein have been shown to predict the risk for major depression one study showed that the risk of major depression increased by 44% for each standard deviation increase in log C reactive protein
people suffering from clinical depression have higher concentrations of the inflammatory biomarkers C reactive protein in il6 by up to 50%