An early, abbreviated TMS protocol applied once daily to the left DLPFC showed antidepressant effects.

“And then they combined the two and started stimulating once a day in this kind of very abbreviated fashion. And lo and behold, some of those depression patients resolved their depression. And back then, and still today, you can go and as a psychiatric patient stay at the National Institute of Mental Health and go through clinical trials to try to get treated. And there were patients who'd been there for months and they were able to be discharged. Because their mood was better, yeah.”