Transcranial magnetic stimulation (TMS) targets specific brain circuitry involved in depression by sending memory signals into the prefrontal cortex.

“It's really that idea that you're laying in that information to the exact right spot. And the signal is a simple signal, but it's a profound one, which is turn on, stay on, remember to stay on. You know, that idea that you're sending this memory signal into the brain and you're doing it in such a way that you're telling the system, you're kind of taking it out of your own hippocampus' hand and you're sending the same signal the hippocampus normally signals out. Now you're sending that signal into the prefrontal cortex and kind of utilizing the brain's own communication style to get it to get out of the state.”