Pro-inflammatory molecules and cytokines can cross the blood-brain barrier and disrupt neurotransmitter production and release, contributing to depressive symptoms.

“inflammation lowers brain dopamine & serotonin and may cause depression.”

“New animated video explaining how inflammation lowers dopamine and serotonin in the brain and may cause depression.”

“inflammation lowers dopamine and serotonin in the brain and may cause depression.”

“The reason these inflammatory molecules and cytoines are able to have these sorts of effects is because they are able to cross over the bloodb brain barrier and disrupt neurotransmitter production and release.”

“this inflammatory mediators are crossing the blood/brain barrier, getting into the brain and, you know, disrupting neurotransmission.”

“first they are able to inhibit the release of neurotransmitters from press synaptic neurons these neurotransmitters play a fundamental role in mood anxiety and motivation and include serotonin norepinephrine and dopamine dopamine levels have been shown to decrease in the brain and a reduction in the activation of reward circuitry occurred in people that were injected with the proinflammatory cyto interfere on gamma but not Placebo”