Andrew Huberman· PhD
Why cortisol hormone? Well, more stress is correlated with more bouts of major depression across the lifespan.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Why cortisol hormone? Well, more stress is correlated with more bouts of major depression across the lifespan.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
How many bouts? Well, it turns out that as you go from having one to two to three, well, when you hit four to five bouts of really intense stressful episodes in life, these tend to be long-term stressful episodes, your risk for major depression goes way up.