Andrew Huberman· PhD
if you sleep deprive somebody one night in just kind of an isolated single night, at the end of that sleep deprivation, they will have an antidepressant effect, but as soon as they fall asleep, they lose it.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
if you sleep deprive somebody one night in just kind of an isolated single night, at the end of that sleep deprivation, they will have an antidepressant effect, but as soon as they fall asleep, they lose it.
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sleep deprivation can improve symptoms of depression.
in a subset of patients with depression if we deprive them of sleep for one night we get this really interesting antidepressant benefit where it helps them