A dramatic elevation in dopamine and norepinephrine relative to baseline promotes neuroplasticity at particular synapses.

“when dopamine and norepinephrine are increased there is a higher probability of strengthening connections where dopamine and norepinephrine are increased and what that means is that later even if levels of dopamine and norepinephrine are not increased if they go back to Baseline it's often the case that if in our prior history or the history of a given set of neurons in our brain there was more dopamine or norepinephrine around it's very likely that the connections where that took place are strengthened and therefore more easily activated”