The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
a colleague of yours um Yamanaka won a Nobel Prize for essentially showing that you can take a skin cell put in a dish give it Yamanaka factors as it were for >> in some cases only three transcription factors and essentially revert that cell to a stem cell and then give it some other transcription factors and turn it into I don't know a neuron or a pancreatic cell.
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if you take uh you know fully differentiated cells for example fibroblast um and you expose them to a particular cocktail of four transcription factors um that the cell reverts to a stem cell like State um and these are called um induced Pur potent stem cells
where they're taking skin cells and they're...you mentioned this generic program where they're throwing in some of these gene factors, that can say to the skin cell, "Hey, I want you to become a stem cell.
Well, the first person to use these factors was Shinya Yamanaka, a Japanese scientist who looked through a lot of different genes and found a set of four factors that if you put them into an adult cell, say, a skin cell, they would go back to being very primitive, so primitive, what we call a pluripotent stem cell that you could then turn those cells into a nerve cell or even regrow an eye in the dish.
We do... I mean, a high school student can do that these days. It's not that difficult. Typically, with science, once you know how something works, it's pretty easy.
these are four different transcription factors that were discovered by Dr. Shinya Yamanaka.