David Sinclair· PhD
Reversing the age of entire mice is not
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Reversing the age of entire mice is not
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And I think the new publication, which is done in more of a wild type, not a progeroid mouse, does show kind of some reversal of the epigenetic clock.