David Sinclair· PhD
Exercise and fasting often yield similar improvements in aging biomarkers. Both boost metabolism, lower inflammation and activate repair pathways.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Exercise and fasting often yield similar improvements in aging biomarkers. Both boost metabolism, lower inflammation and activate repair pathways.
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But do we slow down aging by fasting and running? Absolutely, no question.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.