David Sinclair· PhD
So typically that means having a late lunch if you skip breakfast or if you prefer to skip dinner uh skip that
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
So typically that means having a late lunch if you skip breakfast or if you prefer to skip dinner uh skip that
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
at least with fasting pointing towards etrf as being marginally better than say just skipping breakfast
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.