Fasting promotes cell repair and shrinkage by increasing AMPK, sirtuins, FOX-O, ATF, and ketones.

“And it's that up sirtuin, down MTOR that is hugely beneficial and turns on all of the body's defenses, the pro chewing up the old proteins, improving insulin sensitivity, giving us more energy, repairing cells, all of that.”

“But together when you're fasting, you'll get the sirtuin activation, which is good for you. And you'll also through lack of amino acids, particularly three of them, leucine, lysine and valine. The body will down-regulate mTOR and it's that up sirtuin, down MTOR that is hugely beneficial and turns on all of the body's defenses, the pro chewing up the old proteins, improving insulin sensitivity, giving us more energy, repairing cells, all of that.”

“But together, when you're fasting, you'll get the sirtuin activation, which is good for you, and you'll also, through lack of amino acids, particularly three of them, leucine, isoleucine, valine, the body will downregulate mTOR, and it's that up sirtuin, down mTOR that is hugely beneficial and turns on all of the body's defenses.”