David Sinclair· PhD
Also showing that people of regular weight, like me, can benefit from fasting, there's a number of studies there.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Also showing that people of regular weight, like me, can benefit from fasting, there's a number of studies there.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
But undoubtedly, the magnitude of any beneficial effects on health in people that already have a healthy body weight are going to be less than on people who are overweight.
But since all the animal studies, the control group is couch potatoes, and we're seeing good effects on the couch potatoes, we can't say, you know, that does apply to humans of normal weight.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.