Fasting can increase serum LDL, potentially indicating LDL's role in substance transport.

“as your LDL is going up your LDL receptors that are picking up LDL from circulation in the liver are going down since the liver is making so much cholesterol it doesn't need to pick up cholesterol from circulation so there is a down regulation of LDL receptors that pick up cholesterol the second thing that's happening is that your bile acid production is going up”

“but you change gears you fast instead then there's going to be more pollicis releasing more fatty acids that's going to ultimately end up in more vldls and those will instead be dropping off the free fatty acids to your tissue remodeling to LDLs resulting in you having high LDL particles and high LDL cholesterol”

“when you are fasting your ldl goes up which is actually something that makes sense in terms of an energy model perspective if you are not taking in calories your body is going to move the fat to your cells from other places or your liver is going to put it into the boats and give you the energy in those ways which is part of how the energy model works”

“the fasting increases serum ldl this is actually you know consistent with your data that you're showing there i mean here it is guys when you fast you're killing yourself according to the lipid hypothesis so you guys decide what you think is going on here it doesn't really make a whole lot of sense to me other than the fact that hey ldl might actually be a part of something like an energy model where it's moving things around the body and isn't actually killing you in the right context”

“ketosis probably increases ldl fasting increases ldl we know that much”

“ketosis probably increases ldl fasting increases ldl we know that much”

“My LDL cholesterol went from 64 to 37 after the fast I mean it went way down”