The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
as your LDL is going up your LDL receptors that are picking up LDL from circulation in the liver are going down since the liver is making so much cholesterol it doesn't need to pick up cholesterol from circulation so there is a down regulation of LDL receptors that pick up cholesterol the second thing that's happening is that your bile acid production is going up
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the other piece of this equation that I think is so interesting that you Illustrated that's hawk was that fasting can increase LDL and there and to talk about that a little bit so fasting is an extreme example of a low-carb diet because when you're fasting you're gonna run out of carbohydrates you know if you're practicing low-carb within probably about 8 to 12 hours if you are a carbajal like maybe in a couple of days so in a 7-day fast in 10 healthy individuals the LDL went up by a whopping 70% 77070 percent
but you change gears you fast instead then there's going to be more pollicis releasing more fatty acids that's going to ultimately end up in more vldls and those will instead be dropping off the free fatty acids to your tissue remodeling to LDLs resulting in you having high LDL particles and high LDL cholesterol
the fasting increases serum ldl this is actually you know consistent with your data that you're showing there i mean here it is guys when you fast you're killing yourself according to the lipid hypothesis so you guys decide what you think is going on here it doesn't really make a whole lot of sense to me other than the fact that hey ldl might actually be a part of something like an energy model where it's moving things around the body and isn't actually killing you in the right context
when you are fasting your ldl goes up which is actually something that makes sense in terms of an energy model perspective if you are not taking in calories your body is going to move the fat to your cells from other places or your liver is going to put it into the boats and give you the energy in those ways which is part of how the energy model works
ketosis probably increases ldl fasting increases ldl we know that much
ketosis probably increases ldl fasting increases ldl we know that much
My LDL cholesterol went from 64 to 37 after the fast I mean it went way down
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.