A 24-hour fast-feed cycle in mice that extends lifespan is equivalent to approximately a 5-day fast in humans.

“"A 24-hour fast–feed cycle in mice that extends lifespan equates to a ~5 day fast in humans."”

“Keep in mind, 16 hours of not eating for a mouse is not even in the solar system as 16 hours of not eating in humans.”

“My concern with time restricted feeding which I practice quite liberally is I'm worried it is not a significant enough deprivation of nutrients in humans in other words I think Sachin 's data is so impressive in mice you know but I think that for a mouse to go 16 hours without eating is an enormous task it might be the equivalent of us not eating for three days”

“a one day maybe it's like a one to one to four ratio so one day mouse fast might be a four or five day fast in in people um but that's not even perfectly true because a mouse you know a mouse will go into ketosis relatively quickly within 24 hours right and a human can go into ketosis that quickly depending on depending on their incoming diet yeah exactly right so so it's not it's not a perfect equivalency but but maybe one to four or five”

“So, I'd say, you know, a day of complete fasting could be equivalent to, like...”