Andrew Huberman· PhD
Metabolic flexibility. You're not you're going from using carbohydrates as fuel to using fatty acids and making ketone bodies as fuel. And that's something that,
Loading…
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Metabolic flexibility. You're not you're going from using carbohydrates as fuel to using fatty acids and making ketone bodies as fuel. And that's something that,
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
I would think because you're spending five days in more of a fasting state, or a fasting-mimicking state, that you are becoming more metabolically flexible because you're switching to being able to oxidize fatty acids and then...so you're being able to kind of switch between carbohydrate, you know, using glucose as the main source of energy and using fatty acids...
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.