Bryan Johnson· Author
The study suggests that the use of intermittent fasting protocols might be risky and unsuitable for teenagers due to potential damage in β cells maturation and insulin production.
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We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
The study suggests that the use of intermittent fasting protocols might be risky and unsuitable for teenagers due to potential damage in β cells maturation and insulin production.
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while in adolescent mice the protocol exerted no positive effects, and led to disrupted blood sugar control due to impaired maturation of the pancreatic β cells.
Time-restricted eating produces fat loss independent of total calories.
A 72-hour fast measurably improves autophagy markers in healthy adults.
One-meal-a-day (OMAD) eating patterns increase all-cause mortality in long-running cohort data.
Eating the largest meal before 3pm improves 24-hour glucose vs. an evening-heavy schedule, calorie-matched.