David Sinclair· PhD
improvement in 4 aging parameters after 23 w of glycine + NAC.
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improvement in 4 aging parameters after 23 w of glycine + NAC.
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Dietary supplementation with glutathione precursors, cysteine and glycine, two-thirds of the molecule, fully restores glutathione synthesis.
Deficient synthesis of glutathione, which is our main antioxidant policeman in the human body, underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation.
So, these authors believe that if you supplement with cysteine and glycine as you age, you can improve your glutathione levels, and that can help ameliorate oxidative stress.
The authors of this paper believe that as we age, the increase in oxidative stress is related to deficiency of cysteine and glycine. And that is because those amino acids are critical to make glutathione.
Supplementation with a combination of glycine and N-acetylcysteine improved glutathione levels, oxidative stress, mitochondrial function, muscle strength, cognition, and more in older individuals.