Andrew Huberman· PhD
And so the immune system is incredibly active in the small intestine to make sure that microbes aren't getting so close, and if they are getting close, there's a response to them to put them back in their right location.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
And so the immune system is incredibly active in the small intestine to make sure that microbes aren't getting so close, and if they are getting close, there's a response to them to put them back in their right location.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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And the immune system is a big factor as well. And the immune system is incredibly active in the small intestine. The small intestine is this really interesting challenge for the host, because it's a tissue that's been... Its purpose is mainly absorptive. And so there has to be flow of a lot of things, a lot of nutrients from the luminal contents into host cells. And so that means the barrier can't be as fortified. And so the immune system is incredibly active in the small intestine to make sure that microbes aren't getting so close, and if they are getting close, there's a response to them to put them back in their right location.