Andrew Huberman· PhD
And they tend to work in a bit of a seesaw fashion, prolactin up, dopamine down, right? Dopamine up, prolactin down. In general, that is the way they work.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
And they tend to work in a bit of a seesaw fashion, prolactin up, dopamine down, right? Dopamine up, prolactin down. In general, that is the way they work.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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The hormone prolactin tends to be antagonistic. It tends to reduce amounts of dopamine or at least when prolactin levels are high, dopamine levels tend to be lower. You observe this after the birth of a new child, you observe this post coitally after mating, in all species, humans and animals. When prolactin is elevated, serotonin tends to be elevated.