Andrew Huberman· PhD
And then the luteinizing hormone kicks on because it's now going to prepare her uterus for the lining to accommodate a pregnancy. So now you start to see estradiol go back, but now, for the first time, progesterone goes up.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
And then the luteinizing hormone kicks on because it's now going to prepare her uterus for the lining to accommodate a pregnancy. So now you start to see estradiol go back, but now, for the first time, progesterone goes up.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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And the corpus luteum starts making three hormones, which include estradiol, I think called inhibin, but the most important hormone, the one that you really need to know about, is that it starts producing very high levels of progesterone.