Andrew Huberman· PhD
Prolactin is mutually inhibitory, as we would say. It's kind of in a push-pull with dopamine. When dopamine levels are high, prolactin levels tend to be low, and when prolactin levels are high, dopamine levels tend to be low.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Prolactin is mutually inhibitory, as we would say. It's kind of in a push-pull with dopamine. When dopamine levels are high, prolactin levels tend to be low, and when prolactin levels are high, dopamine levels tend to be low.
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I always think of uh dopamine and prolactin is kind of a seesaw relationship dopamine's up prolactin is down
So if you're increasing your dopamine too much, you're going to overflow and then you're going to have that wave crash too much.
Just as testosterone and estrogen need to be in the proper ratios, dopamine and prolactin need to be in the appropriate ratios.