Andrew Huberman· PhD
So yes, I said it, hormones modulate neuromodulators. I sort of said it twice on purpose. And this is a dramatic and potent effect.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So yes, I said it, hormones modulate neuromodulators. I sort of said it twice on purpose. And this is a dramatic and potent effect.
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And vitally important is the fact that which neural circuits are active and which neural circuits are likely to be less active at any given moment, depends on two major categories of chemicals. It depends on hormones and it depends on so-called neuromodulators.