Bryan Johnson· Author
Evidence says 101.3°F is the trigger for heat shock proteins. But that assumes a starting temp of 98.6°F (a +2.7°F increase).
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Evidence says 101.3°F is the trigger for heat shock proteins. But that assumes a starting temp of 98.6°F (a +2.7°F increase).
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Based upon our deep dive of the evidence, we think the answer leans toward it being an absolute.