Andrew Huberman· PhD
One can be your ratio of androgens to estrogens is off, and that needs addressed. Another one can be it's inhibiting the conversion of your progesterone to that other type of progesterone, the 5-alpha, 3-alpha, that we talked about earlier that's helping with your sleep and your brain, and your calmness. And that's definitely an effect. Another one is depending on the type of supplement or med, they inhibit different isoenzymes of that 5-alpha reductase.