Rhonda Patrick· PhD
So one in five genes is under control of cortisol.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
So one in five genes is under control of cortisol.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And it peaks about the time we wake up... [Satchin]: Yeah. [Rhonda]: ...or something like that, right? [Satchin]: It rises when we wake up. So that promotes alertness, and melatonin is the opposite, it [laughs] promotes sleep. [Rhonda]: Right. And it also...I mean, cortisol regulates... in itself, it's regulating... [Satchin]: Yeah, huge amount. [Rhonda]: …you know, 20% of protein-coding genes.
cortisol is a hormone that changes like 25% of the human genome. Many of those genes involved in inflammation...